Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies (Details Textual)

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Commitments and Contingencies (Details Textual) - USD ($)
1 Months Ended 12 Months Ended
May 02, 2016
Nov. 02, 2015
Oct. 08, 2015
Oct. 07, 2016
Aug. 19, 2016
May 31, 2016
Feb. 29, 2016
Oct. 19, 2015
Dec. 31, 2016
Jun. 30, 2016
Apr. 30, 2016
Jan. 31, 2016
Dec. 31, 2015
Oct. 31, 2015
Aug. 31, 2015
Loss Contingencies [Line Items]                              
Class of Warrant or Right, Number of Securities Called by Warrants or Rights           107,802                  
Class of Warrant or Right, Exercise Price of Warrants or Rights           $ 7.50                  
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities           $ 1,000,000                  
Business Combination, Consideration Transferred, Equity Interests Issued and Issuable           750,000                  
Deferred Compensation Liability, Classified, Noncurrent                 $ 87,500       $ 0    
Milestone Payment Description               The amended milestone payments are as follows: (i) commencement of Phase III Study for first licensed drug/product within the United States, Europe, China or Japan - $150,000; (ii) submission of the first NDA within the United States - $500,000; and (iii) receipt of first marketing approval for sale of a license product in the United States - $600,000.              
Mr. Louis [Member]                              
Loss Contingencies [Line Items]                              
Severance Costs       $ 100,000                      
Separation Agreement Description       Pursuant to the Separation Agreement, Mr. Ploth will be permitted to exercise 25% of the options to purchase common stock granted to him in December 2015, or 50,000 shares, until May 2020.                      
Moleculin LLC [Member]                              
Loss Contingencies [Line Items]                              
Payments for Other Fees           306,186                  
Patent Law Firm [Member] | Minimum Fee and patent Expenses [Member]                              
Loss Contingencies [Line Items]                              
Contractual Obligation, Total                         42,504 $ 65,504  
Bonwick Capital Partners LLC [Member]                              
Loss Contingencies [Line Items]                              
Letter Agreements Terms             the Company agreed to: a) pay success fees equal to 7% of the gross proceeds from any form of financing; and b) issue five-year warrants to purchase 7% of the Companys equity securities sold with a cashless exercise provision, exercisable at 125% of the price per share of the Companys common stock paid by investors in the transaction. In addition, the Company agreed to reimburse Bonwick for all of its out-of-pocket expenses incurred in connection with the offering, not to exceed $25,000, and fees and expenses of their counsel not to exceed $100,000.                
Success Fee Percentage             7.00%                
Class of Warrant or Right, Percentage of Securities Called by Warrants or Rights             7.00%                
Class of Warrant or Right, Exercise Price Percentage Threshold             125.00%                
Payments for Underwriting Expense             $ 50,000                
Bonwick Capital Partners LLC [Member] | IPO [Member]                              
Loss Contingencies [Line Items]                              
Reimburement of Expenses           6,266                  
Payments of Stock Issuance Costs           $ 646,872                  
Class of Warrant or Right, Number of Securities Called by Warrants or Rights           107,802                  
Class of Warrant or Right, Exercise Price of Warrants or Rights           $ 7.50                  
Bonwick Capital Partners LLC [Member] | Maximum [Member]                              
Loss Contingencies [Line Items]                              
Reimbursement Payable, Offering Costs             25,000                
Reimbursement Payable, Fees and Expenses of Counsel             $ 100,000                
MD Anderson [Member] | Minimum Fee and patent Expenses [Member]                              
Loss Contingencies [Line Items]                              
Contractual Obligation, Total     $ 98,108                   $ 45,000 98,108  
MD Anderson [Member] | Minimum Annual Royalty [Member]                              
Loss Contingencies [Line Items]                              
Contractual Obligation, Total     65,504                        
Chief Executive Officer [Member]                              
Loss Contingencies [Line Items]                              
Officers' Compensation                 300,000            
Deferred Compensation Liability, Classified, Noncurrent                 $ 87,500 $ 12,500          
Chief Financial Officer and Executive Vice President [Member]                              
Loss Contingencies [Line Items]                              
Officers' Compensation         $ 250,000                    
Deferred Compensation Arrangement with Individual, Maximum Contractual Term         3 years                    
Chief Financial Officer and Executive Vice President [Member] | Employee Stock Option [Member]                              
Loss Contingencies [Line Items]                              
Deferred Compensation Arrangement with Individual, Shares Issued         400,000                    
Deferred Compensation Arrangement with Individual, Exercise Price         $ 5.85                    
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period         10 years                    
Patent and Technology License Agreement [Member]                              
Loss Contingencies [Line Items]                              
Contractual Obligation, Total                     $ 91,186 $ 175,000   $ 125,000  
Payments for Royalties   $ 125,000                          
License Agreement, Maintenance Fee $ 20,000                            
License Agreement, Maintenance Fee Annual Increase 10,000                            
Payments for Other Fees     300,000                        
License Agreement, Maintenance Fee - Maximum Payable Per Year $ 100,000                            
Patent and Technology License Agreement [Member] | Servicing Fee payable [Member]                              
Loss Contingencies [Line Items]                              
Contractual Obligation, Due First Anniversary April 2, 2013                             $ 10,000
Contractual Obligation, Due Second Anniversary                             20,000
Contractual Obligation, Due Third Anniversary                             40,000
Contractual Obligation, Due Fourth Anniversary                             60,000
Contractual Obligation, Due Fifth Anniversary                             80,000
Contractual Obligation, Due Sixth Anniversary                             100,000
Patent and Technology License Agreement [Member] | Minimum Annual Royalty [Member]                              
Loss Contingencies [Line Items]                              
Contractual Obligation, Due in Next Fiscal Year, After Product Approval                             200,000
Contractual Obligation, Due in Second Year, After Product Approval                             400,000
Contractual Obligation, Due in Third Year, After Product Approval                             $ 600,000
Patent and Technology License Agreement [Member] | Letter Agreement [Member]                              
Loss Contingencies [Line Items]                              
Payments for Other Fees     $ 691,186